البرولاكتين هو هرمون مهم للصحة الإنجابية للمرأة. يصف الطبيب اختبار البرولاكتين إذا كان من الصعب الحمل مع عدم انتظام الدورة الشهرية.
Ukrain ,ukrainegate. 3. November , 2021 _ health
تحليل البرولاكتين في حد ذاته بسيط للغاية ، حيث يتضمن أخذ عينة من الدم الوريدي متبوعة باختبارات معملية. ومع ذلك ، للحصول على النتيجة الأكثر دقة ، سوف تحتاج إلى الاستعداد وتحديد اليوم المناسب للدراسة مع طبيبك. يجدر اختبار مستويات البرولاكتين في حالة آلام الصدر والتوقف المفاجئ عن الدورة الشهرية – تكلفة التحليل منخفضة ، والنتائج هي أساس العلاج المناسب.
When prolactin diagnosis is required
Prolactin, known as lactotropic hormone, belongs to a group of very important peptides. Prolactin has long ceased to be considered a hormone exclusively responsible for the development of lactation. It was found that its participation can be noted in immune, reproductive, metabolic, osmoregulatory processes and even stress control processes.
Indications for the determination of prolactin in women are:
difficulty conceiving;
irregular menstruation;
pain during sexual intercourse;
hypersensitivity of the mammary glands;
anovulatory cycles;
loss or decrease in libido;
secretion of fluid from the nipples (in the absence of lactation);
benign changes in the mammary glands (mastopathy, cysts);
suspected pituitary adenoma (in both sexes);
headaches and visual disturbances.
Under physiological conditions, prolactin increases in women in the second period of the menstrual cycle, during pregnancy, breastfeeding, as well as in both sexes as a result of exercise, severe stress, on the background of hypoglycemia and slightly with age.
How to prepare for the examination
The most effective analysis is a two-stage one, which consists in taking blood in the morning and then in an hour. However, most often the blood is taken once, and this is enough to obtain accurate data.
Blood sampling is performed in the morning on an empty stomach, after eight hours of sleep and preferably until 10:00.
Two days before the test, be sure to exclude any physical activity, as well as sexual intercourse. The day before, it is important not to expose yourself to stressful situations, as any overexertion can distort the results of the study.
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Characteristics of prolactin research and complexity of analysis
Prolactin is a hormone that has a pronounced circadian rhythm, so its maximum release is observed during a night’s sleep. In addition, the hormone fluctuates according to the levels of estrogen and progesterone, it goes like this: an increase in the first phase of the menstrual cycle – a decrease in the second; increase during pregnancy – decrease after childbirth; increase during breastfeeding.
In the case of an increase in prolactin in periods when its concentration should remain normal, the presence of hyperprolactinemia is implied. In this case, the study of prolactin continues, but by a different method – with the use of special drugs. So, first a blood sample is taken to determine the standard level of the hormone. Then the patient takes drugs based on metoclopramide or cerucal, after 60-120 minutes, a repeat blood sample is taken to determine the concentration of prolactin.
Interpretation of analysis results: norm and pathology
Hormone levels for women vary depending on in which phase of the cycle the test is performed;
is 20 μg / l.
The indicators described below may (but do not always) indicate the following problems:
- 5-25 ng / ml – the rate of prolactin
- more than 25 ng / ml – irregular menstruation and anovulatory cycles;*
- more than 50 ng / ml – complete cessation of menstruation;
- above 100 ng / ml – risk of pituitary tumor.
Decreased levels of prolactin in the blood is called hypoprolactinemia. Fortunately, this condition is quite rare and is caused by insufficient activity of the pituitary gland.
To date, standard control ranges for many laboratory determinations have not been established. Due to the fact that these values depend on many factors, such as age, sex, study population, method of determination, type of laboratory and its diagnostic capabilities. Therefore, it is strongly recommended that after receiving the test results, do not try to decipher them yourself, and consult a doctor .
source : Ukrgate
see more : Everything a Woman Needs to Know About Breast Mastopathy!