Kiev. Ukraine. Ukraine Gate – January 12, 2021 – Health
Scientists from the University of Cincinnati made a conclusion that the effects of stress on the expectant mother increase the likelihood of developing the disease in the child – perhaps even throughout the life of the child.
According to the study, psychosocial factors that create stress – such as lack of social support, loneliness, marital status or loss of a loved one – can lead to mutations in the mitochondrial DNA of their child and become a precursor to a number of diseases, including asthma, obesity and hyperactivity syndrome. with attention deficit and autism.
As part of their research, the scientists sequenced the mitochondrial genome and found mutations in 365 placental samples from pregnant women in Boston and New York from 2013 to 2018. A multivariate regression model was used to study the effect of stress during maternal life on the number of gene mutations in the mitochondrial genome of the placenta.
It has been found that women who experience increased psychosocial stress – which can range from sexual violence, domestic violence or serious trauma to imprisonment, physical or mental illness and family difficulties – have had more placental mutations in mitochondria during their lifetime.